I had such a hard time getting through this book, and this is coming from someone who liked God Emperor of Dune. I think so much of the beginning is banter back and forth about what to do about the Honored Matres, the story wore out on me. Although the ending gave everything the story had set up, with a huge cliffhanger of course, I thought it was dragged out.
I don't know if it has been awhile since I read the last book, but I felt that much of the writing in the book was really choppy. There didn't seem to be any elegant passages of description or lengthy introspection. It made it difficult to read when in between talking the characters were heaving little snippets of thought in which they were accusing the other character in their mind of something, but then saying something different out loud. Really, the most of the book seems like it takes place in three rooms where two people are talking.
Chapterhouse: Dune didn't deliver for me.